NCAA1 League Games/Schedule (2021-2022)
| Iowa St. Games/Schedule | |||||||
| Regular Season | |||||||
| Nov. 9, 2021 | Day 1 | Omaha - Iowa St. (10) | 38-65  | ||||
| Nov. 15, 2021 | Day 7 | S.Dakota St. - Iowa St. (10) | 56-75 | ||||
| Nov. 18, 2021 | Day 10 | Iowa St. (10) - Drake | 98-76 | ||||
| Nov. 21, 2021 | Day 13 | Southern - Iowa St. (10) | 55-96 | ||||
| Nov. 27, 2021 | Day 17 | Penn St. - Iowa St. (10) | 59-93 | ||||
| Nov. 26, 2021 | Day 18 | Charlotte - Iowa St. (10) | 59-75 | ||||
| Nov. 28, 2021 | Day 20 | Iowa St. (10) - UMass | 76-71 | ||||
| Dec. 2, 2021 | Day 24 | Iowa St. (10) - LSU (9) | 60-69  | ||||
| Dec. 5, 2021 | Day 27 | Longwood - Iowa St. (10) | 56-94 | ||||
| Dec. 8, 2021 | Day 30 | Iowa (8) - Iowa St. (10) | 70-77 | ||||
| Dec. 12, 2021 | Day 34 | UNI - Iowa St. (10) | 69-70 | ||||
| Dec. 19, 2021 | Day 41 | PVAMU - Iowa St. (10) | 39-108 | ||||
| Jan. 2, 2022 | Day 52 | WVU - Iowa St. (10) | 72-88 | ||||
| Jan. 5, 2022 | Day 55 | Iowa St. (10) - Oklahoma (21) | 81-71 | ||||
| Jan. 8, 2022 | Day 58 | TCU - Iowa St. (10) | 47-78 | ||||
| Jan. 11, 2022 | Day 61 | Iowa St. (10) - Kansas St. | 73-70 | ||||
| Jan. 15, 2022 | Day 65 | Iowa St. (10) - OK State | 74-60 | ||||
| Jan. 19, 2022 | Day 69 | Texas (7) - Iowa St. (10) | 66-48 | ||||
| Jan. 23, 2022 | Day 73 | Iowa St. (10) - Baylor (4) | 61-87 | ||||
| Jan. 26, 2022 | Day 76 | Kansas - Iowa St. (10) | 62-77 | ||||
| Jan. 29, 2022 | Day 79 | Iowa St. (10) - Texas Tech | 86-65 | ||||
| Feb. 2, 2022 | Day 83 | Kansas St. - Iowa St. (10) | 55-70 | ||||
| Feb. 5, 2022 | Day 86 | OK State - Iowa St. (10) | 58-76 | ||||
| Feb. 12, 2022 | Day 93 | Iowa St. (10) - TCU | 93-70 | ||||
| Feb. 16, 2022 | Day 97 | Iowa St. (10) - Texas (7) | 48-73 | ||||
| Feb. 19, 2022 | Day 100 | Oklahoma (21) - Iowa St. (10) | 67-89 | ||||
| Feb. 23, 2022 | Day 104 | Iowa St. (10) - Kansas | 85-59 | ||||
| Feb. 26, 2022 | Day 107 | Texas Tech - Iowa St. (10) | 55-71 | ||||
| Feb. 28, 2022 | Day 109 | Baylor (4) - Iowa St. (10) | 87-62 | ||||
| Mar. 5, 2022 | Day 113 | Iowa St. (10) - WVU | 74-57 | ||||
| Mar. 11, 2022 | Day 119 | WVU - Iowa St. (10) | 60-66 | ||||
| Mar. 12, 2022 | Day 120 | Texas (7) - Iowa St. (10) | 82-73 | ||||
| National Tournament Day 1 | |||||||
| Mar. 18, 2022 | Day 122 | UT Arlington - Iowa St. (10) | 71-78 | ||||
| National Tournament Day 2 | |||||||
| Mar. 20, 2022 | Day 123 | Georgia - Iowa St. (10) | 44-67 | ||||
| National Tournament Day 3 | |||||||
| Mar. 25, 2022 | Day 124 | Creighton - Iowa St. (10) | 76-68 | ||||
