| Mississippi St. Games/Schedule |
| Regular Season |
| Nov. 6, 2018 | Round 1 | SE Missouri St. - Mississippi St. (4) | 53-88 |
| Nov. 9, 2018 | Round 4 | Mississippi St. (4) - Virginia | 72-44 |
| Nov. 15, 2018 | Round 10 | Lamar - Mississippi St. (4) | 53-104 |
| Nov. 18, 2018 | Round 13 | Coppin St. - Mississippi St. (4) | 38-110 |
| Nov. 21, 2018 | Round 16 | Furman - Mississippi St. (4) | 41-106 |
| Nov. 24, 2018 | Round 19 | Jackson St. - Mississippi St. (4) | 38-105 |
| Nov. 28, 2018 | Round 23 | Mississippi St. (4) - UALR | 98-63 |
| Dec. 2, 2018 | Round 27 | Mississippi St. (4) - Texas (23) | 67-49 |
| Dec. 6, 2018 | Round 31 | Marquette (18) - Mississippi St. (4) | 82-87 |
| Dec. 14, 2018 | Round 38 | Mississippi St. (4) - S.Mississippi | 86-42 |
| Dec. 18, 2018 | Round 42 | Mississippi St. (4) - Oregon (7) | 74-82 |
| Dec. 20, 2018 | Round 44 | Mississippi St. (4) - Washington | 103-56 |
| Dec. 30, 2018 | Round 51 | La-Lafayette - Mississippi St. (4) | 36-104 |
| Jan. 3, 2019 | Round 54 | Mississippi St. (4) - Arkansas | 93-69 |
| Jan. 6, 2019 | Round 57 | Kentucky (17) - Mississippi St. (4) | 71-86 |
| Jan. 10, 2019 | Round 61 | Georgia - Mississippi St. (4) | 71-80 |
| Jan. 14, 2019 | Round 65 | Mississippi St. (4) - Auburn | 85-59 |
| Jan. 17, 2019 | Round 68 | S.Carolina (15) - Mississippi St. (4) | 74-89 |
| Jan. 24, 2019 | Round 75 | Mississippi St. (4) - Florida | 90-42 |
| Jan. 27, 2019 | Round 78 | Mississippi - Mississippi St. (4) | 49-80 |
| Jan. 31, 2019 | Round 82 | Mississippi St. (4) - LSU | 68-35 |
| Feb. 3, 2019 | Round 85 | Mississippi St. (4) - Alabama | 65-49 |
| Feb. 10, 2019 | Round 92 | Tennessee - Mississippi St. (4) | 63-91 |
| Feb. 14, 2019 | Round 96 | Missouri - Mississippi St. (4) | 75-67 |
| Feb. 17, 2019 | Round 99 | Mississippi St. (4) - Texas A (14) | 92-64 |
| Feb. 21, 2019 | Round 103 | Mississippi St. (4) - Mississippi | 80-66 |
| Feb. 24, 2019 | Round 106 | Vanderbilt - Mississippi St. (4) | 70-86 |
| Feb. 28, 2019 | Round 110 | LSU - Mississippi St. (4) | 56-76 |
| Mar. 3, 2019 | Round 113 | Mississippi St. (4) - S.Carolina (15) | 68-64 |
| Mar. 8, 2019 | Round 118 | Tennessee - Mississippi St. (4) | 68-83 |
| Mar. 9, 2019 | Round 119 | Missouri - Mississippi St. (4) | 56-71 |
| Mar. 10, 2019 | Round 120 | Arkansas - Mississippi St. (4) | 70-101 |
| National Tournament Round 1 |
| Mar. 22, 2019 | Round 128 | Southern - Mississippi St. (4) | 46-103 |
| National Tournament Round 2 |
| Mar. 24, 2019 | Round 129 | Clemson - Mississippi St. (4) | 61-85 |
| National Tournament Round 3 |
| Mar. 29, 2019 | Round 130 | Arizona St. (22) - Mississippi St. (4) | 53-76 |
| Quarter-Finals |
| Mar. 31, 2019 | Round 131 | Oregon (7) - Mississippi St. (4) | 88-84 |
